Apparently, Science Magazine is turning 125, and they’re celebrating with a special online collection of articles.

In a special collection of articles published beginning 1 July 2005, Science Magazine and its online companion sites celebrate the journal’s 125th anniversary with a look forward — at the most compelling puzzles and questions facing scientists today.

125 questions from Science

The collection includes, among others, staff essays on 25 big questions facing science in the next 25 years.